reduce blood flow to the extremities, making fingers and toes feel unusually cold.
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This is usually not dangerous, but persistent pain, major color changes, or worsening circulation problems should be discussed with a doctor.
6. Shortness of Breath or Wheezing
Metoprolol mainly acts on beta-1 receptors in the heart, but at higher doses it can also affect receptors in the lungs.
People with asthma or other breathing conditions may be more sensitive.
Seek medical advice if you develop:
new wheezing
increasing shortness of breath
chest tightness
difficulty