These symptoms can have many possible causes, so proper medical assessment is important rather than assuming that swelling is caused by a particular organ problem.
6. Blood Clots
Sudden swelling in one leg — particularly when accompanied by redness, warmth, or pain — can be a sign of a blood clot such as deep vein thrombosis (DVT).
DVT can become life-threatening if part of the clot breaks away and travels to the lungs.
Seek urgent medical attention if swelling develops suddenly in one leg, particularly when it occurs with pain,